- July 22nd, 8:30AM-5:00PM EST, Friday,2022
- Room 310, The Baltimore Convention Center, Baltimore, Maryland, USA
- Link for virtual
- Registration
Machine learning advances are used in self-driving cars, speech recognition systems, and translation software. However, the COVID-19 pandemic has highlighted the urgency of translating such advances to the domain of biomedicine. Such a pivot requires new machine learning methods to build long-term vaccines and therapeutic strategies, predict immune avoidance, and better repurpose small molecules as drugs.
The objective of the ICML Workshop on Computational Biology (WCB) is to highlight how machine learning approaches can be tailored to making both translational and basic scientific discoveries with biological data. Practitioners at the intersection of computation, machine learning, and biology are in a unique position to frame problems in biomedicine, from drug discovery to vaccination risk scores, and WCB will showcase such recent research. Commodity lab techniques lead to the proliferation of large complex datasets and require new methods to interpret these collections of high-dimensional biological data, such as genetic sequences, cellular features or protein structures and imaging datasets. These data can be used to make new predictions towards clinical response, uncover new biology, or aid in drug discovery.
This workshop aims to bring together interdisciplinary machine learning researchers working in areas such as computational genomics; neuroscience; metabolomics; proteomics; bioinformatics; cheminformatics; pathology; radiology; evolutionary biology; population genomics; phenomics; ecology, cancer biology; causality; representation learning and disentanglement to present recent advances and open questions to the machine learning community. We especially encourage interdisciplinary submissions that might not neatly fit into one of these categories.
Deadline for paper submissions: May 8th 13th 2022 (11:59 PM Pacific Time)
Deadline for edit submissions: May 16th, 2022 (11:59 PM Pacific Time)
Reviewer deadline: May 30th 2022
Notification of acceptance: June 13th, 2022
Camera-ready deadline: July 16th, 2022
Workshop date: July 22nd, 2022
We invite extended abstracts dealing with novel algorithms and computational approaches that are robust,
scalable to high-dimensional data, and provide interpretable models of biological systems. These can be applications of ML methods or
bioinformatics approaches to biological and biomedical data or novel approaches that enable new analyses. Papers will be presented in poster
format and some will be selected for oral presentation (contributed and spotlight talks).
Through invited talks and presentations by the participants, this workshop will bring together current advances in Computational Biology and set
the stage for continuing interdisciplinary research discussions.
Submission
All novel Computational Biology approaches are of interest to the workshop. We welcome original abstracts on preliminary ideas and findings in the following format:
* Times below are in EDT
8:30 - 8:40 am | Opening Remarks (Cassandra Burdziak) | ||
Session 1 (Chair: Cassandra Burdziak) | |||
8:40 - 9:20 am | Tamara Broderick | ||
Predicting and maximizing genomic variant discovery via Bayesian nonparametrics | |||
9:20 - 9:45 am | Damiano Sgarbossa | ||
Generative power of a protein language model trained on multiple sequence alignments | [Paper] | ||
9:45 - 10:00 am | Spotlight talks | ||
Daniel Hesslow - RITA: a study on scaling up generative protein sequence models | [Paper] | ||
Amir Alavi - Learning batch-invariant representations with domain adaptation in large scale proteomics data | |||
Haiyi Mao & Minxue Jia - COEM: cross-modal embedding for metacell identification | [Paper] | ||
10:00 - 10:30 am | Coffee break | ||
Session 2 (Chair: Cameron Park) | |||
10:30 - 11:10 am | Jean Fan | ||
Towards a common coordinate framework: alignment of spatially resolved omics data | |||
11:10 - 11:35 am | Haoran Zhang | ||
BayesTME: a reference-free Bayesian method for end-to-end analysis of spatial transcriptomic data | |||
11:35 - 12:00 pm | Spotlight talks | ||
Hannes Stärk - EquiBind: geometric deep learning for drug binding structure prediction | |||
Sophie Jaro - Learning to rank metabolites across datasets | |||
James Zou - 7-UP: generating in silico CODEX from a small set of immunofluorescence markers | [Paper] | ||
Andrew J. Jung - RTfold: RNA secondary structure prediction using deep learning with domain inductive bias | [Paper] | ||
Haotian Cui (STREAMED) - A deep learning framework for estimating cell-specific kinetic rates of RNA velocity | |||
12:00 - 1:30pm | Poster session 1 | ||
Session 3 (Chair: Pascal Notin) | |||
1:30 - 2:20 pm | Panel discussion: Mohammad AlQuraishi, Elana Fertig, Patrick Schwab, Neeha Zaidi | ||
ML that matters: Discovering new drugs and treatments for challenging diseases using AI | |||
2:20 - 3:00 pm | Spotlight talks | ||
Achille Nazaret - Probabilistic basis decomposition for characterizing temporal dynamics of gene expression | [Paper] | ||
Kieran Elmes - SNVformer: an attention-based deep neural network for GWAS data | [Paper] | ||
Christopher Hendra - Extracting part of signal representation from direct RNA squiggle for modification detection | |||
Hagai M Kariti - A mechanistic probabilistic model of genomic compartments | |||
Kevin Wu - TCR-BERT: learning the grammar of T-cell receptors for flexible antigen-binding analyses | [Paper] | ||
Yu Li - Interpretable RNA foundation model from unannotated data for highly accurate RNA structure and function predictions | |||
Pooja Kathail - Assessing the utility of genomic deep learning models for disease-relevant variant effect prediction | [Paper] | ||
Yanan Long - Molecular fingerprints are a simple yet effective solution to the drug–drug interaction problem | |||
3:00 - 4:30 pm | Poster session 2 | ||
Session 4 (Chair: Yubin Xie) | |||
4:30 - 4:55 pm | Cameron Park | ||
DIISCO: dynamic intercellular interactions in single cell transcriptomics | |||
4:55 - 5:20 pm | Zhenqin Wu | ||
SPACE-GM: geometric deep learning of disease-associated microenvironments from multiplex spatial protein profiles | |||
5:20 - 5:30 pm | Award ceremony and closing remarks (Yubin Xie) |
*Listed alphabetically
Associate Professor
EECS Department at Massachusetts Institute of Technology
Assistant Professor
Biomedical Engineering Department at Johns Hopkins University
*Listed alphabetically
Assistant Professor
Columbia University
Director of The Research Program in Quantitative Sciences
Johns Hopkins Kimmel Cancer Center
Director
Machine Learning and Artificial Intelligence at GSK
Assistant Professor
Johns Hopkins Medicine
ICML Workshop on Computational Biology aims to foster an inclusive and welcoming community.
If you have any questions, comments, or concerns, please reach out to workshopcompbio@gmail.com.
We are also featuring other workshops that you might find helpful for diversity and inclusion.
Queer in AI
Diversity Fellowship
We are pleased to announce that we will continue our Diversity Fellowship for students this year.
Awards include a free virtual or in-person workshop registration. We encourage applications from underrepresented groups. The deadline is July 15th. Apply here.
Dana Pe’er: mskcc.org/research/ski/labs/dana-pe-er
Debora Marks: https://www.deboramarkslab.com/
Elham Azizi: https://www.azizilab.com/
Sandhya Prabhakaran: sandhyaprabhakaran.com
Abdoulaye Baniré Diallo: labo.bioinfo.uqam.ca
Alexander Anderson: labpages.moffitt.org/andersona/
Wesley Tansey: http://wesleytansey.com
Julia E. Vogt: mds.inf.ethz.ch/team/detail/julia-vogt/
Yubin Xie: yux2009@med.cornell.edu
Cassandra Burdziak: cnb3001@med.cornell.edu
Amine Remita: remita.amine@courrier.uqam.ca
Mafalda Dias: mafalda_dias@hms.harvad.edu
Mauricio Tec: mauriciogtec@utexas.edu
Cameron Park: cyp2111@columbia.edu
Achille Nazaret: aon2108@columbia.edu
Pascal Notin: pascal.notin@cs.ox.ac.uk
Steffan Paul: steffanpaul@g.harvard.edu
Abdoulaye Banire Diallo, Université du Québec à Montréal
Achille Nazaret, Columbia University
Adam Gayoso, UC Berkeley
Adrian Heilbut, logphase research
Ahmed Halioui, Mt Intelligent Machines
Alice Bizeul, ETHZ
Amine Remita, Université du Québec à Montréal
Andreas Kirsch, University of Oxford
Anne Siegel, CNRS
Bishnu Sarker, Inria
Bo Yuan, Harvard University
Cameron Park, Columbia University
Cassandra Burdziak, Memorial Sloan Kettering Cancer Center
Chensu Xie, Weill Cornell Medicine
Chetanya Pandya, 2seventy bio
Christopher Garay, Paradigm4
Debora Marks, Harvard Medical School
Doron Haviv, Cornell
Elham Azizi, Columbia University
Elior Rahmani, UCLA
Elisabetta De Maria, Université Côte d'Azur
Freddie Bickford Smith, University of Oxford
Gilles Gut, ETH Zürich
Han Yuan, Calico Life Sciences
Hayda Almeida, UQAM
Imant Daunhawer, ETH Zurich
Jan Brauner, University of Oxford
Khalil Ouardini, Owkin
Lood van Niekerk, Harvard Medical School
Luis Rueda, University of Windsor
Mafalda Dias, Harvard Medical School
Manu Setty, SKI
Matthew Peterson, Paradigm4
Mauricio Tec, University of Texas at Austin
Mengting Gu, Visa Research
Mervin Fansler, MSKCC
Mika Jain, Stanford University
Mohammad Lotfollahi, Helmholtz Zentrum München
Nazim Bouatta, Harvard
Neil Band, University of Oxford
Niina Haiminen, IBM T. J. Watson Research Center
Pascal Notin, University of Oxford
Peter Koo, Cold Spring Harbor Laboratory
Ričards Marcinkevičs, ETH Zurich
Romain Lopez, UC Berkeley
Sabeur Aridhi, LORIA
Sandhya Prabhakaran, Moffitt Cancer Center
Sarvesh Nikumbh, Imperial College London and MRC London Institute of Medical Sciences
Sheng Liu, Indiana University School of Medicine
Smita Krishnaswamy, Yale University
Steffan Paul, Harvard Medical School
Thomas Sutter, ETH Zurich
Vianne Gao, Weill Medical College
Victor Greiff, Department of Immunology, University of Oslo
Warith Eddine DJEDDI, FST Manar
Xiang Niu, Memorial Sloan Kettering Cancer Center
Yubin Xie, Memorial Sloan Kettering Cancer Center
Yuelin Shi, California Institute of Technology