- Decision is out✨
- Camera-ready deadline: July 21th, 2023
- Workshop time: Saturday, July 29th, 2023
- Location: Hawaii Convention Center (Room 314), Honolulu, Hawai'i, USA
Each year, machine learning (ML) advances are successfully translated to develop systems we now use regularly, such as speech recognition platforms or translation software. The COVID-19 pandemic has highlighted the urgency for translating these advances to the domain of biomedicine. Biological data has unique properties (high dimensionality, degree of noise and variability), and therefore poses new challenges and opportunities for methods development. To facilitate progress toward long-term therapeutic strategies or basic biological discovery, it is critical to bring together practitioners at the intersection of computation, ML, and biology. The ICML Workshop on Computational Biology (WCB) will highlight how ML approaches can be tailored to making both translational and basic scientific discoveries with biological data, such as genetic sequences, cellular features or protein structures and imaging datasets, among others. This workshop thus aims to bring together interdisciplinary ML researchers working in areas such as computational genomics; neuroscience; metabolomics; proteomics; bioinformatics; cheminformatics; pathology; radiology; evolutionary biology; population genomics; phenomics; ecology, cancer biology; causality; representation learning and disentanglement to present recent advances and open questions to the machine learning community. We especially encourage interdisciplinary submissions that might not neatly fit into one of these categories.
        
        Deadline for paper submissions: May 17th 19th 2023 (11:59 PM Pacific Time)
        Reviewer deadline: June 9th 2023 
        Notification of acceptance: June 19th, 2023
        Camera-ready deadline: July 21th, 2023
        Workshop date: July 29th, 2023 
    
We invite extended abstracts dealing with novel algorithms and computational approaches that are robust, 
	      scalable to high-dimensional data, and provide interpretable models of biological systems. These can be applications of ML methods or 
	      bioinformatics approaches to biological and biomedical data or novel approaches that enable new analyses. Papers will be presented in poster 
	      format and some will be selected for oral presentation (contributed and spotlight talks). 
	      Through invited talks and presentations by the participants, this workshop will bring together current advances in Computational Biology and set 
	      the stage for continuing interdisciplinary research discussions.
        
Submission
 
All novel Computational Biology approaches are of interest to the workshop.
	      In addition to the main track, we will hold a special track on “Explainability in Biological data” which will feature submissions focused on interpretable ML approaches and their applications for biological data. This will include inherently explainable and interpretable ML approaches, post-hoc interpretations of existing models, ways to evaluate the quality of explanations, limitations and failure modes of existing methods, and visualization strategies for analyzing models.
	     
 We welcome original abstracts on preliminary ideas and findings in the following format:
     
            
            * Times below are in HST (GMT-10) 
            
                
| 9:00 - 9:05AM | Opening Remarks | ||
| Session 1 (Chair: Cameron Park) | |||
| 9:05 - 9:40AM | Michael Bronstein | ||
| Geometric ML for designing new molecules | |||
| 9:40 - 10:00AM | William Beardall | ||
| Genomic Interpreter: A Hierarchical Genomic Deep Neural Network with 1D Shifted Window Transformer | [Paper] | ||
| 10:00 - 10:15AM | Spotlight talks | ||
| Claudia Skok Gibbs - A Variational Inference Approach to Single-Cell Gene Regulatory Network Inference using Probabilistic Matrix Factorization | [Paper] | ||
| Eric D Sun - Graph reinforcement and smoothing for improved spatial gene expression prediction | [Paper] | ||
| Jos Torge - DiffHopp: A Graph Diffusion Model for Novel Drug Design via Scaffold Hopping | [Paper] | ||
| 10:15 - 10:45AM | Coffee break | ||
| Session 2 (Chair: Lingting Shi) | |||
| 10:45 - 11:05AM | Rui Yang | ||
| HiC2Self: Self-supervised Hi-C contact map denoising | [Paper] | ||
| 11:05 - 11:25AM | Sukwon Yun | ||
| Single-cell RNA-seq data imputation using Feature Propagation | [Paper] | ||
| 11:25 - 11:50AM | Spotlight talks | ||
| Kristina Ulicna - Learning dynamic image representations for self-supervised cell cycle annotation | [Paper] | ||
| Nhat Khang Ngo - Multiresolution Graph Transformers and Wavelet Positional Encoding for Learning Hierarchical Structures | [Paper] | ||
| Cuong Q Nguyen - Molecule-Morphology Contrastive Pretraining for Transferable Molecular Representation | [Paper] | ||
| Kavi Gupta - Improved modeling of RNA-binding protein motifs in an interpretable neural model of RNA splicing | |||
| Simon V Mathis - Normal Mode Diffusion: Towards Dynamics-informed Protein Design | [Paper] | ||
| 11:50 - 12:50PM | Poster session 1 | ||
| 12:50 - 1:30PM | Lunch break | ||
| Session 3 (Chair: Bianca M. Dumitrascu) | |||
| 1:30 - 2:05PM | Bin Yu | ||
| Veridical data science for reliable, reproducible, and transparent data analysis and decision-making | |||
| 2:05 - 2:25PM | Spotlight talks | ||
| Zhongliang Zhou - Explaining the blackbox: Unraveling Protein Language Model's Learning Mechanisms for Kinase-Specific Phosphorylation Prediction | |||
| Jun Xia - Why Deep Models Often Cannot Beat Non-deep Counterparts on Molecular Property Prediction? | |||
| Alex M Tseng - Hierarchically branched diffusion models for scientific discovery | [Paper] | ||
| Kemal Inecik - scARE: Attribution Regularization for Single Cell Representation Learning | [Paper] | ||
| 2:25 - 3:00PM | Invited talk: Su-In Lee | ||
| 3:00 - 4:00PM | Poster session 2 | ||
| 4:05 - 4:15PM | Award ceremony and concluding remarks | ||
*Listed alphabetically
 
            
            
                    DeepMind Professor of Artificial Intelligence
                    Department of Computer Science
                    University of Oxford
                
 
            
            
                    Professor
                    Paul G. Allen School of Computer Science
                    University of Washington, Seattle
                
 
            
            
                    Chancellor's Distinguished Professor
                    Department of Statistics & EECS
                    UC Berkeley
                
        
	 
	   ICML Workshop on Computational Biology aims to foster an inclusive and welcoming community.    
	   If you have any questions, comments, or concerns, please reach out to workshopcompbio@gmail.com. 
     
	    
        
        We are also featuring other workshops that you might find helpful for diversity and inclusion. 	      
        Queer in AI 
	      
        
	
  
    
        
Dana Pe’er (mskcc.org/research/ski/labs/dana-pe-er)
Debora Marks (https://www.deboramarkslab.com/)
Alexander Anderson  (labpages.moffitt.org/andersona/)
Elham Azizi (https://www.azizilab.com/ )
Sandhya Prabhakaran  (sandhyaprabhakaran.com)
Abdoulaye Baniré Diallo (labo.bioinfo.uqam.ca )
Wesley Tansey  (http://wesleytansey.com)  
Bianca Dumitrascu (https://computational-morphogenomics-group.github.io)
Maria Brbic (https://brbiclab.epfl.ch/)
	
        
Yubin Xie: yux2009@med.cornell.edu 
Cassandra Burdziak: burdziac@mskcc.org 
Mafalda Dias: mafalda.dias@crg.eu
Cameron Park: cyp2111@columbia.edu
Pascal Notin: pascal.notin@cs.ox.ac.uk 
Joy Fan:	lf2684@columbia.edu 
Ruben Weizman:	rubenweitzman@gmail.com 
Lingting Shi: ls3456@columbia.edu 
Siyu He: sh3846@columbia.edu 
Yinuo Jin: yj2589@columbia.edu 
	    
            Achille Nazaret, Columbia University
            Adam Gayoso, UC Berkeley
            Adrian Heilbut, logphase research
            Ahmed Halioui, Mt Intelligent Machines
            Ahmet Coskun, Georgia Tech
            Alice Bizeul, ETHZ
            Alyssa Morrow, UC Berkeley
            Amine Remita, Université du Québec à Montréal
            Amy Xie, Memorial Sloan Kettering Cancer Center
            Anastasiya Belyaeva, Google Research
            Arnav Das, University of Washington
            Ayshwarya Subramanian, Broad Institute
            Behrooz Tahmasebi, MIT
            Benjamin Gallusser, EPFL
            Benjamin Wesley, Columbia University
            Bianca Dumitrascu, Columbia University
            Bishnu Sarker, Inria
            Bo Yuan, Harvard University
            Brian Trippe, Columbia University
            Cameron Park, Columbia University
            Cassandra Burdziak, Memorial Sloan Kettering Cancer Center
            Chandana Rajesh, Cold Spring Harbor Laboratory
            Charles Harris, University of Cambridge
            Chenlian Fu, Memorial Sloan Kettering Cancer Center
            Chetanya Pandya, 2seventy bio
            Christopher Garay, Paradigm4
            Dana Pe'er, Memorial Sloan Kettering Cancer Center
            Debora Marks, Harvard University
            Delasa Aghamirzaie, Natera
            Ece Ozkan, MIT
            Ehsan Hajiramezanali, Genentech
            Elham Azizi, Columbia University
            Elior Rahmani, UCLA
            Engelbert Mephu Nguifo, Université  Clermont Auvergne, CNRS, LIMOS
            Evan Seitz, Cold Spring Harbor Laboratory
            Eyal Itskovits, GSK.ai
            Fabian Theis, Helmholtz Zentrum München
            Filippo Utro, IBM THOMAS J. WATSON RESEARCH CENTER
            Freddie Bickford Smith, University of Oxford
            Gabriele Scalia, Genentech
            Han Spinner, Harvard
            Hayda Almeida, UQAM
            Ignacio Vazquez-Garcia, Memorial Sloan Kettering Cancer Center / Columbia University
            Ilyes Baali, Memorial Sloan Kettering Cancer Center
            Jan Brauner, University of Oxford
            Jason Dou, University of Pittsburgh
            Jessica White, Memorial Sloan Kettering Cancer Center
            Jill Gallaher, Moffitt Cancer Center
            Joy Fan, Columbia University
            Justin Hong, Columbia University
            Kangway Chuang, Genentech Research and Early Development
            Kevin Hoffer-Hawlik, Columbia University
            Keyur Shah, Massachusetts General Hospital
            Khanh Dinh, Columbia University
            Kyle Swanson, Stanford University
            Lea Goetz, GSK.ai
            Lei Xiong, MIT
            Lingting Shi, Columbia University
            Lingyi Cai, Columbia University
            Lood van Niekerk, Harvard Medical School
            Luis Rueda, University of Windsor
            Manu Setty, SKI
            Maria Brbic, Stanford University
            Mario Wieser, Genedata AG
            Matthew Peterson, Paradigm4
            Mervin Fansler, Memorial Sloan Kettering Cancer Center
            Mingxuan Zhang, Columbia University
            Mohammad Lotfollahi, Helmholtz Zentrum München
            Mostafa Karimi, Amazon
            Namkyeong Lee, Korea Advanced Institute of Science and Technology
            Nathan Rollins, Seismic Therapeutic
            Nazim Bouatta, Harvard University
            Nicolas Beltran, Columbia University
            Petko Fiziev, Illumina, Inc
            Philip Fradkin, Vector Institute
            Pierre Boyeau, UC Berkeley
            Pooja Kathail, UC Berkeley
            Ragothaman Yennamalli, SASTRA Deemed University
            Ričards Marcinkevičs, ETH Zurich
            Rishabh Anand National, University of Singapore
            Romain Lopez, Genentech and Stanford
            Rui Yang, Memorial Sloan Kettering Cancer Center
            Russell Kunes, Columbia University
            Sabeur Aridhi, LORIA
            Sairam Behera, Baylor College of Medicine
            Sandhya Prabhakaran, Moffitt Cancer Center
            Sepideh Maleki, Genentech
            Sheng Liu, Indiana University School of Medicine
            Shiyi Yang, UC Berkeley
            Shouvik Mani, Columbia University
            Shreshth Malik, University of Oxford
            Shuhao Zhang, EPFL
            Simon Mathis, University of Cambridge
            Siyu He, Columbia University
            Smita Krishnaswamy, Yale University
            Somesh Mohapatra, Caterpillar Inc
            Soufiane Mourragui, Hubrecht Institute
            Soumya Kundu, Stanford University
            Srivamshi Pittala, Katana Graph Inc
            Stephen Zhang, University of Melbourne
            Surag Nair, Stanford University
            Talip Ucar, AstraZeneca
            Tianming Zhou, Carnegie Mellon University
            Umberto Lupo, EPFL
            Victor Greiff, University of Oslo
            Warith Eddine,  DJEDDI FST Manar
            Xiang Niu, Memorial Sloan Kettering Cancer Center
            Xue Long Zhao, University of Pennsylvania
            Xuecong Fu, Carnegie Mellon University
            Yanay Rosen, Stanford University
            Yinuo Jin, Columbia University
            Yongju Lee, Genentech
            Yubin Xie, Memorial Sloan Kettering Cancer Center
            Yue Wu, Stanford University
            Ziqi Tang, Cold Spring Harbor Laboratory